This article presents the results of experimental studies evaluating the effectiveness of five insecticides used against aphids (Aphidoidae) that damage fruit and berry plants. The tested preparations included Mospilan Star, Medkiller, Kapitan, Nurel Asia, and Tepic. The experiment was conducted in 2024–2025 in the orchards of the Suzak District, Jalal-Abad Region. Each insecticide was applied at the manufacturer’s recommended dosage, and aphid populations were recorded at three intervals after treatment. Based on the experimental data, Nurel Asia and Mospilan Star demonstrated the highest effectiveness against aphids. The study highlights the importance of selecting effective and environmentally safe means of protecting orchard crops from pests.